For those who care about glucosamine and are willing to play with their own health:
“…Therefore, the production of the collagen by the chondrocytes is facilitated by relaxin. Good quality collagen is produced in the presence of relaxin, which binds with proteogylcan to form strong resilient cartilage. Together with the deactivation of the collagenase by the glucosamine sulfate, homeostasis of the cartilage regeneration and degeneration are maintained and the joint is returned to its formal healthy state. Accordingly, relaxin enhances the effect of glucosamine sulfate in retarding and restoring osteodegenerative changes of the joints.”
“The relaxin hormone will alleviate these conditions since relaxin acts to effect collagen formation and collagen remodelling. Relaxin will alleviate the generalized pain and tenderness by elongating muscles and accentuating joint laxity by remodelling connective tissue (e.g ligaments, tendons, bone, etc.) via collagen changes. This expected effect is based on many studies that have observed that pregnant women have elongated pelvic area muscles, and increased joint laxity resulting from the remodelling effect induced by relaxin“
